The Promethazine codeine syrup Diaries

The codeine and promethazine in Promethazine with Codeine Oral Remedy may enhance the frequency of seizures in patients with seizure Issues, and will enhance the possibility of seizures happening in other scientific options connected to seizures.

Constipation is a common aspect influence of both equally codeine and hydrocodone use and sometimes carries on during treatment method. Individuals may perhaps take stool softeners and improve their fluid ingestion to aid lower this side outcome.

Because of the risks of habit, abuse, and misuse with opioids, even at recommended doses [see Warnings and Safety measures (five.1) ], reserve Promethazine with Codeine Oral Option for use in adult patients for whom the key benefits of cough suppression are expected to outweigh the risks, and in whom an ample assessment on the etiology on the cough is produced.

Discontinuation of a concomitantly made use of cytochrome P450 2D6 inhibitor may bring about a lessen in codeine plasma concentration and an increase in active metabolite morphine plasma concentration which could raise or lengthen adverse reactions and will cause likely deadly respiratory melancholy.

Not less than a single Loss of life was documented within a nursing infant who was exposed to high amounts of morphine in breast milk because the mom was an extremely-fast metabolizer of codeine.

tell your physician When you've got or have at any time had an enlarged prostate (a male reproductive gland); glaucoma (a affliction through which elevated tension in the eye can cause gradual loss of vision); seizures; ulcers; blockage within the passage involving the abdomen and intestine; blockage from the bladder; asthma or other lung disorder; snooze apnea; most cancers;any problem that influences the creation of blood cells as part of your bone marrow; or coronary heart or liver ailment.

The phosphate salt of codeine happens as white, needle-shaped crystals or white crystalline powder. Codeine phosphate is freely soluble in h2o and a bit soluble in Alcoholic beverages. The molecular body weight is 406.37. Its molecular components is C18H21NO3•H3PO4 • ½ H2O, and it's the following chemical framework.

The next adverse reactions are actually recognized through clinical experiments, in the literature, or for the duration of publish-acceptance usage of codeine and/or promethazine.

Make sure you Keep to the directions carefully, for the reason that continuing constipation may result in additional serious complications.

Convey to your medical professional if you have at any time had any strange or allergic response to this medicine or any other medicines. Also explain to your wellbeing treatment Skilled if you have any other sorts of allergy symptoms, for example to foods, dyes, preservatives, or animals. For non-prescription items, browse the label or bundle ingredients very carefully.

No evidence of tumorigenicity was observed in male and female mice at codeine dietary doses up to 400 mg/kg/day (about comparable to 45 times the MRHD on the mg/m2 basis).

Abdomen or bowel blockage (which include paralytic ileus)—Really should not be used in clients Using these conditions.

Making use of Alcoholic beverages or tobacco with particular medicines might also trigger interactions to happen. The subsequent interactions are Promethazine codeine syrup actually chosen on the basis of their likely significance and therefore are not automatically all-inclusive.

Working with alcohol or tobacco with sure medicines may cause interactions to come about. The next interactions happen to be chosen on the basis of their opportunity importance and so are not necessarily all-inclusive.